You may have missed my previous reply. Backing up the VM and restoring it on the destination will take care of different folders, so will the OVF export/import. However, in case of an OVF export/import, the target VM will receive new UUIDs and MAC addresses. With simply copying the files/folders you will - besides requiring more disk space for the transport, and inflated disks in case of thin-provisioning being used - have to either manually edit the VM's configuration file on the target, and/or re-attach the virtual disks, because the datastore's UUIDs will most likely be different in the other location.
André